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Stage III adult non-Hodgkin lymphoma
Pronunciation
Definition 1
Stage III is divided into stages III, IIIE, IIIS, and IIIE+S. In stage III, cancer is found in one or more lymph node groups above and below the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen). In stage IIIE, cancer is found in lymph node groups above and below the diaphragm and outside the lymph nodes in a nearby organ or area. In stage IIIS, cancer is found in lymph node groups above and below the diaphragm and in the spleen. In stage IIIE+S, cancer is found in lymph node groups above and below the diaphragm, outside the lymph nodes in a nearby organ or area, and in the spleen. (NCI Dictionary)
Definition 2
Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S). (NCI Thesaurus)
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