Health / Medical Topics |
STAT5A wt Allele
Human STAT5A wild-type allele is located in the vicinity of 17q11.2 and is approximately 24 kb in length. This allele, which encodes signal transducer and activator of transcription 5A protein, is involved in both cytokine and growth factor-stimulated signaling and suppression of apoptosis. (NCI Thesaurus)
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This gene plays a role in signal transduction and activation of transcription. It is involved in the immune response via stimulation of…
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This gene is involved in signal transduction and activation of transcription. It plays a role in regulation of T-helper cell differentiation. …
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STATs, Signal Transducers and Activators of Transcription, are transcription factors that are phosphorylated by JAK kinases in response to cytokine activation to…
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An orally bioavailable inhibitor of signal transducer and activator of transcription 3 (STAT3), with potential antineoplastic activity. STAT3 inhibitor OPB-51602 inhibits the…
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