STAT5B/RARA Fusion Gene

A fusion gene that results from a complex rearrangement of 17q21 that fuses the 5' portion of the STAT5B gene to exon 3 of the RARA gene. This chromosomal aberration may be associated with acute promyelocytic leukemia. (NCI Thesaurus)

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STAT5B wt Allele

Human STAT5B wild-type allele is located in the vicinity of 17q11.2 and is approximately 77 kb in length. This allele, which encodes…

STAT5B Gene

This gene is involved in signal transduction and activation of transcription. It plays a role in the immune response via stimulation of…

STAT5A wt Allele

Human STAT5A wild-type allele is located in the vicinity of 17q11.2 and is approximately 24 kb in length. This allele, which encodes…

STAT5A Gene

This gene plays a role in signal transduction and activation of transcription. It is involved in the immune response via stimulation of…

STAT4 wt Allele

Human STAT4 wild-type allele is located within 2q32.2-q32.3 and is approximately 122 kb in length. This allele, which encodes signal transducer and…

STAT4 Gene

This gene is involved in signal transduction and activation of transcription. It plays a role in regulation of T-helper cell differentiation. …