Health / Medical Topics |
STAT5B wt Allele
Human STAT5B wild-type allele is located in the vicinity of 17q11.2 and is approximately 77 kb in length. This allele, which encodes signal transducer and activator of transcription 5B protein, is involved in cytokine and growth factor-mediated signal progression. In some acute promyelocytic leukemias, the wild-type allele is fused to the retinoic acid receptor-alpha allele. A homozygous missense mutation in this gene can result in Laron type dwarfism II. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in signal transduction and activation of transcription. It plays a role in the immune response via stimulation of…
Human STAT5A wild-type allele is located in the vicinity of 17q11.2 and is approximately 24 kb in length. This allele, which encodes…
This gene plays a role in signal transduction and activation of transcription. It is involved in the immune response via stimulation of…
Human STAT4 wild-type allele is located within 2q32.2-q32.3 and is approximately 122 kb in length. This allele, which encodes signal transducer and…
This gene is involved in signal transduction and activation of transcription. It plays a role in regulation of T-helper cell differentiation. …
Human STAT3 wild-type allele is located in the vicinity of 17q21 and is approximately 75 kb in length. This allele, which encodes…