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XII
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The cardinal number that is the sum of eleven and one
Synonyms:
Classified under:
Nouns denoting quantities and units of measure
Hypernyms ("XII" is a kind of...):
large integer (an integer equal to or greater than ten)
Hyponyms (each of the following is a kind of "XII"):
boxcars ((usually plural) an expression used when two dice are thrown and both come up showing six spots)
II. (adjective)
Sense 1
Meaning:
Denoting a quantity consisting of 12 items or units
Synonyms:
12; dozen; twelve; xii
Classified under:
Similar:
cardinal (being or denoting a numerical quantity but not order)
Context examples:
Test of the intrinsic (factors VIII, IX, XI, and XII) and common (fibrinogen, prothrombin, factors V and X) pathways of coagulation in which a mixture of plasma and phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides) is recalcified and the time required for the appearance of fibrin strands measured.
(Partial Thromboplastin Time, NLM, Medical Subject Headings)
This cascade begins with the activation of factor XII and the release of platelet factor 3 (PF3) from damaged platelets.
(Intrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)
In addition, indisulam also inhibits carbonic anhydrases (CA), especially isoforms IX and XII that are involved in aqueous humor production and are highly overexpressed in some types of cancers.
(Indisulam, NCI Thesaurus)
Activated factor XII cleaves and actives factor XI and prekallikrein (PK).
(Intrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)
